Vitiligo treatment: Substances/Drugs that may cause photosensitivity

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*Reactions occur frequently 

The following substances may cause photosensitivity reactions if taken while having vitiligo light treatment:

Anticancer Drugs

*Dacarbazine (DTIC-Dome)

Fluorouracil (Fluoroplex; and others)

Methotrexate (Mexate; and others)

Procarbazine (Matulane)

Vinblastine (Velban) 


Tricyclic Antidepressants 


Antihistamines

Cyproheptadine (Periactin)

Diphenhydramine (Benadryl; and others) 


Antimicrobials

*Demeclocycline (Declomycin;and others)

Griseofulvin (Fulvicin-U/F;and others)

*Nalidixic acid (NegGram)

Tetracyclines

Sulfanamides 


Antiparasitic Drugs

*Bithionol (Bitin)

Pyrvinium pamoate (Povan)

Quinine (many manufacturers) 


Antipsychotic Drugs 


Diuretics

Acetazolamide (Diamox)

Amiloride (Midamor)

Furosemide (Lasix)

Metolazone (Diulo; Zaroxolyn)

Quinethazone (Hydromox)

Thiazides 


Hypoclycemics

Acetohexamide (Dymelor)

Chlorpropamide (Diabinese; Insulase)

Glipizide (Glucotrol)

Glyburide (DiaBeta; Micronase)

Tolazamide (Tolinase)

Tolbutamide (Orinase; and others) 


Nonsteroidal anti-inflammatory

Ketoprofen (Orudis)

Naproxen (Naprosyn)

Phenylbutazone (Butazolidin;others)

Piroxicam (Feldene)

Sulindac (Clinoril) 


Sunscreens

6-acetoxy-2,4,-dimethyl-m-dioxane (preservative in sunscreens)

Benzophenones (Aramis;Clinique; and others)

Cinnamates (Aramis;Estee Lauder; and others)

Oxybenzone (Eclipse;PreSun; and others)

PABA esters (Eclipse;Block Out; Sea & Ski; and others)

Para-aminobenzoic acid (PABA - Pabagel;

Pabanol; PreSun; and others) 


Others

*Amiodarone (Cordarone)

*Bergamot oil, oils of citron, lavender,

lime, sandalwood, cedar (used in many perfumes and cosmetics; also topical exposure to citrus rind oils)

Benzocaine

Captopril (Capoten)

Carbamazepine (Tegretol)

Contraceptives, oral

Disopyramide (Norpace)

Gold salts (Myochrysine; Solganol)

Hexachlorophene (pHisoHex; and others)

Isotretinoin (Accutane)

6-methylcoumarin (used in perfumes,

shaving lotions, and sunscreens)

Musk ambrette (used in perfumes)

Quinidine sulfate and gluconate


(from Medical Letter 28, Issue 713, 1986) 

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