Polypeptides and the skin...

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Polypeptides are molecules made of a specific sequence of aminoacids. Polypeptides are biologically potent substances of prime importance, which include drugs, hormones, transmitters. Examples of peptide hormones in the body include: oxytocin, vasopressin, angiotensin II, insulin, and many others. 

Some of the functions of polypeptides include: 1) They function as enzymes which are essential for life. 2) They are essential structural components of cells and tissues. 3) They form immunoglobulines and hormones. 5) They can function as biochemical messengers with multiple functions essential to regulate the work of cells and tissues. 

Regulation of the effects of many essential factors for skin growth and normal function includes control of expression of specific growth-factor receptors. The skin cell cycle is also controlled by the intracellular concentrations of cyclic nucleotides, small molecules which are formed and broken down inside the skin cells as a response to external signals acting on the skin cell membrane. A compound known as cyclic AMP is believed to be the intracellular agent or '2nd messenger' of those molecules  i.e. catecholamines and polypeptides, which do not themselves penetrate the surface of cells. Some polypeptides stimulate epidermal cell division and regeneration. Some of them have a complex effect stimulating epidermal growth and wound healing.

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